Drug Information

Drug General Information
Drug ID
D09CKZ
Former ID
DNC012984
Drug Name
AM-411
Drug Type
Small molecular drug
Indication Discovery agent Investigative [531004]
Structure
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2D MOL

3D MOL
Formula
C26H34O2
Canonical SMILES
CC1=CCC2C(C1)C3=C(C=C(C=C3O)C45CC6CC(C4)CC(C6)C5)OC2(C)<br />C
InChI
1S/C26H34O2/c1-15-4-5-21-20(6-15)24-22(27)10-19(11-23(24)28-25(21,2)3)26-12-16-7-17(13-26)9-18(8-16)14-26/h4,10-11,16-18,20-21,27H,5-9,12-14H2,1-3H3/t16?,17?,18?,20-,21-,26?/m1/s1
InChIKey
RPBMPWGKZFLMFN-OKFSJJLXSA-N
PubChem Compound ID
9799945
Target and Pathway
Target(s) Cannabinoid receptor 2 Target Info Inhibitor [531004]
Cannabinoid receptor 1 Target Info Inhibitor [531004]
KEGG Pathway Neuroactive ligand-receptor interactionhsa04015:Rap1 signaling pathway
Neuroactive ligand-receptor interaction
Retrograde endocannabinoid signaling
PANTHER Pathway Endogenous cannabinoid signaling
Pathway Interaction Database N-cadherin signaling events
Reactome Class A/1 (Rhodopsin-like receptors)
G alpha (i) signalling eventsR-HSA-373076:Class A/1 (Rhodopsin-like receptors)
G alpha (i) signalling events
WikiPathways GPCRs, Class A Rhodopsin-like
Small Ligand GPCRs
GPCR ligand binding
GPCR downstream signalingWP455:GPCRs, Class A Rhodopsin-like
BDNF signaling pathway
GPCR downstream signaling
GPCRs, Other
References
Ref 531004J Med Chem. 2010 Aug 12;53(15):5656-66.Heteroadamantyl cannabinoids.
Ref 531004J Med Chem. 2010 Aug 12;53(15):5656-66.Heteroadamantyl cannabinoids.

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