Drug Information

Drug General Information
Drug ID
D09DDQ
Former ID
DIB014502
Drug Name
FUB-130
Synonyms
FUB-130; FUB-132; FUB-250; FUB-465; FUB-86; UCL-1860; UCL-2065; UCL-2283; H3 antagonists, Bioprojet/Berlin Free University/INSERM/UCL
Drug Type
Small molecular drug
Indication Neurological disease [ICD9: 338, 338.2, 410, 782.3,780; ICD10:I21, I22, R52, R52.1-R52.2, R60.9, G89] Investigative [538775]
Company
BioProjet; Societe Civile de Recherche
Structure
Download
2D MOL

3D MOL
Formula
C8H14N2O
InChI
InChI=1S/C8H14N2O/c1-2-11-5-3-4-8-6-9-7-10-8/h6-7H,2-5H2,1H3,(H,9,10)
InChIKey
RSHKAUMLIJVWFJ-UHFFFAOYSA-N
PubChem Compound ID
9989449
PubChem Substance ID
14967801, 44040773, 77078849, 103856743, 104034796, 135650292, 225089306, 233543181, 242095949, 246959660
Target and Pathway
Target(s) Histamine H3 receptor Target Info Antagonist [543673]
KEGG Pathway Neuroactive ligand-receptor interaction
Reactome Histamine receptors
G alpha (i) signalling events
WikiPathways Monoamine Transport
GPCRs, Class A Rhodopsin-like
GPCR ligand binding
GPCR downstream signaling
References
Ref 538775(http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 1260).
Ref 543673(http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Target id: 264).

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