Drug Information

Drug General Information
Drug ID
D09FTJ
Former ID
DIB006356
Drug Name
TTP-054
Synonyms
Glucagon-like peptide 1 receptor modulator (oral, type 2 diabetes) TransTech Pharma
Indication Type 2 diabetes [ICD9: 250; ICD10:E11] Phase 2 [524023]
Company
TransTech Pharma Inc
Target and Pathway
Target(s) Glucagon-like peptide 1 receptor Target Info Modulator [544232]
KEGG Pathway cAMP signaling pathway
Neuroactive ligand-receptor interaction
Insulin secretion
Reactome Glucagon-like Peptide-1 (GLP1) regulates insulin secretion
G alpha (s) signalling events
Glucagon-type ligand receptors
WikiPathways GPCRs, Class B Secretin-like
Integration of energy metabolism
GPCR ligand binding
GPCR downstream signaling
References
Ref 524023ClinicalTrials.gov (NCT01665352) A Study to Evaluate Safety and Efficacy of TTP054 for 12 Weeks in Subjects With Type 2 Diabetes. U.S. National Institutes of Health.
Ref 544232Small Molecule Drug Discovery at the Glucagon-Like Peptide-1 Receptor. Exp Diabetes Res. 2012; 2012: 709893.

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