Drug General Information
Drug ID	D09FWP
Former ID	DNC005585
Drug Name	6-(2-Hydroxy-phenyl)-naphthalen-2-ol
Drug Type	Small molecular drug
Indication	Discovery agent		Investigative	[527584]
Structure		Download 2D MOL 3D MOL
Formula	C16H12O2
Canonical SMILES	C1=CC=C(C(=C1)C2=CC3=C(C=C2)C=C(C=C3)O)O
InChI	1S/C16H12O2/c17-14-8-7-11-9-13(6-5-12(11)10-14)15-3-1-2-4-16(15)18/h1-10,17-18H
InChIKey	SMFVAKMYNVSVKJ-UHFFFAOYSA-N
PubChem Compound ID	11368353
Target and Pathway
Target(s)	Estrogen receptor beta	Target Info	Inhibitor	[527584]
KEGG Pathway	Estrogen signaling pathway
	Prolactin signaling pathway
Pathway Interaction Database	Plasma membrane estrogen receptor signaling
	Validated nuclear estrogen receptor beta network
	Validated nuclear estrogen receptor alpha network
Reactome	Nuclear Receptor transcription pathway
WikiPathways	SIDS Susceptibility Pathways
	Ovarian Infertility Genes
	Integrated Pancreatic Cancer Pathway
	Nuclear Receptors
References
Ref 527584	J Med Chem. 2005 Jun 16;48(12):3953-79.ERbeta ligands. 3. Exploiting two binding orientations of the 2-phenylnaphthalene scaffold to achieve ERbeta selectivity.
Ref 527584	J Med Chem. 2005 Jun 16;48(12):3953-79.ERbeta ligands. 3. Exploiting two binding orientations of the 2-phenylnaphthalene scaffold to achieve ERbeta selectivity.

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