Drug Information

Drug General Information
Drug ID
D09GEK
Former ID
DNCL002360
Drug Name
ASP3026
Drug Type
Small molecular drug
Indication Late-stage B-cell lymphoma [ICD9: 140-199, 202.8, 210-229; ICD10:C00-C75, C7A, C7B, C81-C86, C85.1, D10-D36, D3A] Phase 1 [523558], [542706]
Company
Astellas Pharma
Structure
Download
2D MOL

3D MOL
Formula
C29H40N8O3S
InChI
InChI=1S/C29H40N8O3S/c1-21(2)41(38,39)27-8-6-5-7-25(27)33-29-31-20-30-28(34-29)32-24-10-9-23(19-26(24)40-4)36-13-11-22(12-14-36)37-17-15-35(3)16-18-37/h5-10,19-22H,11-18H2,1-4H3,(H2,30,31,32,33,34)
InChIKey
MGGBYMDAPCCKCT-UHFFFAOYSA-N
PubChem Compound ID
25134326
PubChem Substance ID
56459493, 85000183, 136350042, 137178958, 152258541, 160647375, 162011670, 163643160, 164042008, 174006526, 174526161, 185998844, 198957018, 223366073, 223382318, 223705201, 224721002, 225848209, 228901602, 244138564, 249896059, 251962969, 252158766, 252160645, 252214890, 252451428, 252470515
Target and Pathway
Target(s) ALK tyrosine kinase receptor Target Info Modulator [542706]
KEGG Pathway Non-small cell lung cancer
WikiPathways Differentiation Pathway
References
Ref 523558ClinicalTrials.gov (NCT01401504) Study of an Investigational Drug, ASP3026, in Patients With Solid Tumors. U.S. National Institutes of Health.
Ref 542706(http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 7740).
Ref 542706(http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 7740).

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