Drug Information

Drug General Information
Drug ID
D09GVB
Former ID
DNC004661
Drug Name
OL-135
Drug Type
Small molecular drug
Indication Pain [ICD9: 338, 356.0, 356.8,780; ICD10:G64, G90.0, R52, G89] Investigative [540704]
Structure
Download
2D MOL

3D MOL
Formula
C21H22N2O2
InChI
InChI=1S/C21H22N2O2/c24-19(14-7-2-1-4-10-17-11-5-3-6-12-17)21-23-16-20(25-21)18-13-8-9-15-22-18/h3,5-6,8-9,11-13,15-16H,1-2,4,7,10,14H2
InChIKey
ILOIOIGZFHGSMS-UHFFFAOYSA-N
PubChem Compound ID
10427006
PubChem Substance ID
15446274, 22768704, 40554674, 49846934, 76704454, 103439500, 134341866, 141515879, 172919341, 178101919, 196409623, 224419517, 227679358, 244652795, 252215946
Target and Pathway
Target(s) Fatty-acid amide hydrolase Target Info Inhibitor [530527]
BioCyc Pathway Anandamide degradation
KEGG Pathway Retrograde endocannabinoid signaling
PANTHER Pathway Anandamide degradation
References
Ref 540704(http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 5235).
Ref 530527J Med Chem. 2010 Jan 14;53(1):230-40.X-ray crystallographic analysis of alpha-ketoheterocycle inhibitors bound to a humanized variant of fatty acid amide hydrolase.

If You Find Any Error in Data or Bug in Web Service, Please Kindly Report It to Dr. Zhou and Dr. Zhang.