TTD | Drug: D09HWZ

Drug General Information
Drug ID	D09HWZ
Former ID	DIB018169
Drug Name	[125I]S70254
Drug Type	Small molecular drug
Indication	Discovery agent		Investigative	[542731]
Structure		Download 2D MOL 3D MOL
Formula	C22H20IN3O2
InChI	InChI=1S/C22H20IN3O2/c1-28-20-10-9-18-22(26-20)17(11-12-24-19(27)13-23)21(25-18)16-8-4-6-14-5-2-3-7-15(14)16/h2-10,25H,11-13H2,1H3,(H,24,27)/i23-2
InChIKey	ZYVDSJZCXRMXGR-FOKFMTIASA-N
PubChem Compound ID	86277839
Target and Pathway
Target(s)	Melatonin receptor	Target Info	Agonist	[532369]
KEGG Pathway	Neuroactive ligand-receptor interaction
KEGG Pathway	Circadian entrainment
Reactome	Class A/1 (Rhodopsin-like receptors)
Reactome	G alpha (i) signalling events
WikiPathways	GPCRs, Class A Rhodopsin-like
	Small Ligand GPCRs
	GPCR ligand binding
	GPCR downstream signaling
References
Ref 542731	(http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 7779).
Ref 532369	New radioligands for describing the molecular pharmacology of MT1 and MT2 melatonin receptors. Int J Mol Sci. 2013 Apr 25;14(5):8948-62.

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Drug Information