Drug Information

Drug General Information
Drug ID
D09JDH
Former ID
DNC001321
Drug Name
Septide
Drug Type
Small molecular drug
Indication Discovery agent Investigative [539326]
Structure
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2D MOL

3D MOL
Formula
C39H53N7O7S
InChI
InChI=1S/C39H53N7O7S/c1-24(2)21-29(36(50)42-27(34(40)48)18-20-54-3)44-38(52)32-15-10-19-46(32)39(53)31(23-26-13-8-5-9-14-26)45-37(51)30(22-25-11-6-4-7-12-25)43-35(49)28-16-17-33(47)41-28/h4-9,11-14,24,27-32H,10,15-23H2,1-3H3,(H2,40,48)(H,41,47)(H,42,50)(H,43,49)(H,44,52)(H,45,51)/t27-,28-,29-,30-,31-,32-/m0/s1
InChIKey
UUZURPUIMYJOIL-JNRWAQIZSA-N
CAS Number
CAS 95693-76-8
PubChem Compound ID
119137
PubChem Substance ID
10238360, 29300090, 49992375, 50112609, 51059171, 57339344, 103146191, 104407627, 117501504, 117570112, 134340366, 134340522, 135074997, 135652460, 163109665, 242480959
Target and Pathway
Target(s) Substance-P receptor Target Info Agonist [537828]
KEGG Pathway Calcium signaling pathway
Neuroactive ligand-receptor interaction
Measles
PANTHER Pathway CCKR signaling map ST
Reactome G alpha (q) signalling events
WikiPathways SIDS Susceptibility Pathways
Gastrin-CREB signalling pathway via PKC and MAPK
Spinal Cord Injury
Peptide GPCRs
GPCR ligand binding
GPCR downstream signaling
References
Ref 539326(http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 2095).
Ref 537828Septide: an agonist for the NK1 receptor acting at a site distinct from substance P. Mol Pharmacol. 1994 Feb;45(2):287-93.

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