Drug Information

Drug General Information
Drug ID
D09KAK
Former ID
DPR000080
Drug Name
NOX-F37
Indication Acute and chronic heart failure [ICD9: 428; ICD10:I50] Preclinical [536372]
Target and Pathway
Target(s) Vasopressin V1a receptor Target Info Antagonist [536372]
KEGG Pathway Calcium signaling pathway
Neuroactive ligand-receptor interaction
Vascular smooth muscle contraction
Reactome Vasopressin-like receptors
G alpha (q) signalling events
WikiPathways GPCRs, Class A Rhodopsin-like
Gastrin-CREB signalling pathway via PKC and MAPK
Peptide GPCRs
GPCR ligand binding
GPCR downstream signaling
References
Ref 536372Emerging drugs for acute and chronic heart failure: current and future developments. Expert Opin Emerg Drugs. 2007 Mar;12(1):75-95.
Ref 536372Emerging drugs for acute and chronic heart failure: current and future developments. Expert Opin Emerg Drugs. 2007 Mar;12(1):75-95.

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