Drug Information

Drug General Information
Drug ID
D09PZO
Former ID
DAP000997
Drug Name
Idoxuridine
Synonyms
Antizona; Dendrid; Emanil; Heratil; Herpesil; Herpid; Herpidu; Herplex; IDU; IDUR; IUDR; IdUrd; Idexur; Idossuridina; Idoxene; Idoxuridin; Idoxuridina; Idoxuridinum; Iducher; Idulea; Iduoculos; Iduridin; Iduviran; Iododeoxyridine; Iododeoxyuridine; Iodoxuridine; Joddeoxiuridin; Kerecid; Kerecide; Ophthalmadine; Spectanefran; Stoxil; Synmiol; Virudox; Herplex liquifilm; Idossuridina [DCIT]; Idu Oculos; Allergan 201; Allergan 211; ID2; LT00440811; SKF 14287; Allergan-211; Dendrid (TN); HERPLEX (TN); Herpe-Gel; Herpes-Gel; Idoxuridina [INN-Spanish]; Idoxuridinum [INN-Latin]; Iododeoxyuridine-125I; Oftan-IDU; SK&F 14287; SK&F-14287; Idoxuridine (JP15/USP/INN); Idoxuridine [USAN:INN:BAN:JAN]; (+)-5-Iodo-2'-deoxyuridine; 1-(2-Deoxy-beta-D-ribofuranosyl)-5-iodouracil; 1-(2-deoxypentofuranosyl)-4-hydroxy-5-iodopyrimidin-2(1H)-one; 1-(2-deoxypentofuranosyl)-5-iodopyrimidine-2,4(1h,3h)-dione; 1-(4-Hydroxy-5-hydroxymethyltetrahydrofuran-2-yl)-5-iodo-1H-pyrimidine-2,4-dione; 1-[(2R,4R,5R)-4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]-5-iodopyrimidine-2,4-dione; 1-[(2R,4R,5S)-4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]-5-iodopyrimidine-2,4-dione; 1-[(2R,4S,5R)-4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]-5-iodopyrimidine-2,4-dione; 1-[(2R,4S,5S)-4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]-5-iodopyrimidine-2,4-dione;1-[(2R,5R)-4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]-5-iodopyrimidine-2,4-dione; 1-[(2S,4R,5S)-4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]-5-iodopyrimidine-2,4-dione; 1-[(2S,4S,5R)-4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]-5-iodopyrimidine-2,4-dione; 1-[(2S,4S,5S)-4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]-5-iodopyrimidine-2,4-dione; 1-[4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]-5-iodopyrimidine-2,4-dione; 1-beta-D-2'-Deoxyribofuranosyl-5-iodouracil; 1.beta.-D-2'-Deoxyribofuranosyl-5-iodouracil; 1beta-D-2'-Deoxyribofuranosyl-5-iodouracil; 2'-Deoxy-5-(iodo-125I)uridine; 2'-Deoxy-5-iodouridine; 2'-deoxy-5-(125i)iodouridine; 5-(125-I)-Iodo-2-deoxyuridine; 5-I-2'-dUrd; 5-IUDR; 5-Iodo-2'-deoxyuridine; 5-Iododeoxyuridine; 5-Iododesoxyuridine; 5-Iodouracil deoxyriboside; 5IUDR; 5IdU
Drug Type
Small molecular drug
Indication Herpes simplex virus infection [ICD9: 54; ICD10:B00] Approved [538467]
Therapeutic Class
Antiviral Agents
Structure
Download
2D MOL

3D MOL
Formula
C9H11IN2O5
Canonical SMILES
C1C(C(OC1N2C=C(C(=O)NC2=O)I)CO)O
InChI
1S/C9H11IN2O5/c10-4-2-12(9(16)11-8(4)15)7-1-5(14)6(3-13)17-7/h2,5-7,13-14H,1,3H2,(H,11,15,16)/t5-,6+,7?/m0/s1
InChIKey
XQFRJNBWHJMXHO-GFCOJPQKSA-N
CAS Number
CAS 54-42-2
PubChem Compound ID
16051928
PubChem Substance ID
24896108, 26596148, 37101787, 57379675, 57654307, 118255095, 124542600, 124542601, 124542602, 131318301, 143394060, 151995635, 179670019, 179673882, 226395809, 245854645, 249719212, 252309529
SuperDrug ATC ID
D06BB01; J05AB02; S01AD01
SuperDrug CAS ID
cas=000054422
Target and Pathway
Target(s) DNA Target Info Binder [534878]
References
Ref 538467FDA Approved Drug Products from FDA Official Website. 2009. Application Number: (NDA) 014169.
Ref 534878Radiopharmaceuticals (Strontium 89) and radiosensitizers (idoxuridine). J Intraven Nurs. 1998 Nov-Dec;21(6):335-7.

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