Drug Information

Drug General Information
Drug ID
D09ROS
Former ID
DIB019365
Drug Name
compound 23
Drug Type
Small molecular drug
Indication Discovery agent Investigative [531413], [541075]
Structure
Download
2D MOL
Formula
C22H26FN5O6S
InChI
InChI=1S/C22H26FN5O6S/c1-22(2,3)34-21(30)27-9-7-13(8-10-27)33-19-17-18(24-12-25-19)28(20(29)26-17)16-6-5-14(11-15(16)23)35(4,31)32/h5-6,11-13H,7-10H2,1-4H3,(H,26,29)
InChIKey
AXLNAZYMBNKFJO-UHFFFAOYSA-N
PubChem Compound ID
54582152
PubChem Substance ID
131276237, 131346380, 178102366
Target and Pathway
Target(s) Glucose-dependent insulinotropic receptor Target Info Agonist [531413]
KEGG Pathway cAMP signaling pathway
Insulin secretion
WikiPathways Incretin Synthesis, Secretion, and Inactivation
References
Ref 531413Bioorg Med Chem Lett. 2011 May 15;21(10):3134-41. Epub 2011 Mar 13.Discovery of fused bicyclic agonists of the orphan G-protein coupled receptor GPR119 with in vivo activity in rodent models of glucose control.
Ref 541075(http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 5740).
Ref 531413Bioorg Med Chem Lett. 2011 May 15;21(10):3134-41. Epub 2011 Mar 13.Discovery of fused bicyclic agonists of the orphan G-protein coupled receptor GPR119 with in vivo activity in rodent models of glucose control.

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