TTD | Drug: D09SFJ

Drug General Information
Drug ID	D09SFJ
Former ID	DIB018874
Drug Name	AR-C126313
Synonyms	compound 71a [PMID: 15078212]; compound 52 [PMID: 18600475]
Drug Type	Small molecular drug
Indication	Discovery agent		Investigative	[527032]
Structure		Download 2D MOL
Formula	C17H12ClN3OS2
InChI	InChI=1S/C17H12ClN3OS2/c1-21-7-12(16(23)20-17(21)22)14-11-4-3-10(18)6-9(11)2-5-13-15(14)19-8-24-13/h2-8,14H,1H3,(H,20,22,23)
InChIKey	ZDHQVQVNOIWLNX-UHFFFAOYSA-N
PubChem Compound ID	22003577
PubChem Substance ID	135649951, 233117735
Target and Pathway
Target(s)	P2Y purinoceptor 2	Target Info	Antagonist	[528677]
KEGG Pathway	Neuroactive ligand-receptor interaction
KEGG Pathway	Inflammatory mediator regulation of TRP channels
NetPath Pathway	IL5 Signaling Pathway
Reactome	G alpha (q) signalling events
	P2Y receptors
	Surfactant metabolism
WikiPathways	Nucleotide GPCRs
	GPCRs, Class A Rhodopsin-like
	Gastrin-CREB signalling pathway via PKC and MAPK
	GPCR ligand binding
	GPCR downstream signaling
References
Ref 527032	Molecular recognition at purine and pyrimidine nucleotide (P2) receptors. Curr Top Med Chem. 2004;4(8):805-19.
Ref 528677	Molecular modeling of the human P2Y2 receptor and design of a selective agonist, 2'-amino-2'-deoxy-2-thiouridine 5'-triphosphate. J Med Chem. 2007 Mar 22;50(6):1166-76. Epub 2007 Feb 16.

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Drug Information