Drug Information

Drug General Information
Drug ID
D09TZM
Former ID
DNC001390
Drug Name
Sulfenamido-sulfonamides
Drug Type
Small molecular drug
Indication Discovery agent Investigative [538055]
Structure
Download
2D MOL

3D MOL
Formula
C27H29NO
Canonical SMILES
CC(C(C1=CC=CC=C1)O)N(C)CC=C2C3=CC=CC=C3CCC4=CC=CC=C42
InChI
1S/C27H29NO/c1-20(27(29)23-12-4-3-5-13-23)28(2)19-18-26-24-14-8-6-10-21(24)16-17-22-11-7-9-15-25(22)26/h3-15,18,20,27,29H,16-17,19H2,1-2H3
InChIKey
BHVGOYREXHCFOE-UHFFFAOYSA-N
CAS Number
CAS 90845-56-0
PubChem Compound ID
65823
PubChem Substance ID
17187671, 43122565, 57315757, 80936500, 85210207, 104334748, 126423493, 127517840, 134340580, 134340641, 135025194, 172820819, 179323333, 235831297
Target and Pathway
Target(s) Carbonic anhydrase II Target Info Inhibitor [538055]
Carbonic anhydrase IV Target Info Inhibitor [538055]
Carbonic anhydrase I Target Info Inhibitor [538055]
KEGG Pathway Nitrogen metabolism
Proximal tubule bicarbonate reclamation
Collecting duct acid secretion
Gastric acid secretion
Pancreatic secretion
Bile secretionhsa00910:Nitrogen metabolism
Proximal tubule bicarbonate reclamationhsa00910:Nitrogen metabolism
NetPath Pathway IL4 Signaling Pathway
EGFR1 Signaling Pathway
Pathway Interaction Database C-MYB transcription factor network
PathWhiz Pathway Gastric Acid Production
Reactome Erythrocytes take up carbon dioxide and release oxygen
Erythrocytes take up oxygen and release carbon dioxide
Reversible hydration of carbon dioxideR-HSA-1237044:Erythrocytes take up carbon dioxide and release oxygen
Reversible hydration of carbon dioxide
WikiPathways Reversible Hydration of Carbon Dioxide
Uptake of Carbon Dioxide and Release of Oxygen by Erythrocytes
Uptake of Oxygen and Release of Carbon Dioxide by ErythrocytesWP2770:Reversible Hydration of Carbon Dioxide
Uptake of Oxygen and Release of Carbon Dioxide by Erythrocytes
References
Ref 538055Sulfenamido-sulfonamides as inhibitors of carbonic anhydrase isozymes I, II and IV. J Enzyme Inhib. 1997 Aug;12(3):175-90.
Ref 538055Sulfenamido-sulfonamides as inhibitors of carbonic anhydrase isozymes I, II and IV. J Enzyme Inhib. 1997 Aug;12(3):175-90.

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