Drug Information
Drug General Information | |||||
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Drug ID |
D09UMA
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Former ID |
DNC004281
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Drug Name |
IMAZODAN
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Drug Type |
Small molecular drug
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Indication | Discovery agent | Terminated | [544637] | ||
Structure |
Download2D MOL |
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Formula |
C13H13ClN4O
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Canonical SMILES |
C1CC(=O)NN=C1C2=CC=C(C=C2)N3C=CN=C3
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InChI |
1S/C13H12N4O/c18-13-6-5-12(15-16-13)10-1-3-11(4-2-10)17-8-7-14-9-17/h1-4,7-9H,5-6H2,(H,16,18)
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InChIKey |
VXMYWVMXSWJFCV-UHFFFAOYSA-N
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PubChem Compound ID | |||||
Target and Pathway | |||||
Target(s) | CGMP-specific 3',5'-cyclic phosphodiesterase | Target Info | Inhibitor | [533555] | |
CGMP-dependent3',5'-cyclic phosphodiesterase | Target Info | Inhibitor | [533555] | ||
CGMP-inhibited 3',5'-cyclic phosphodiesterase A | Target Info | Inhibitor | [526726] | ||
References | |||||
Ref 526726 | J Med Chem. 1992 Feb 21;35(4):620-8.3,4-Dihydroquinolin-2(1H)-ones as combined inhibitors of thromboxane A2 synthase and cAMP phosphodiesterase. | ||||
Ref 533555 | J Med Chem. 1984 Sep;27(9):1099-101.Cardiotonic agents. 1. 4,5-Dihydro-6-[4-(1H-imidazol-1-yl)phenyl]-3 (2H)-pyridazinones: novel positive inotropic agents for the treatment of congestive heart failure. |
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