TTD | Drug: D09UVB

Drug General Information
Drug ID	D09UVB
Former ID	DIB020017
Drug Name	HTMT
Synonyms	histamine-trifluoromethyl-toluidine; histamine-trifluoromethyltoluide; HTFMT
Drug Type	Small molecular drug
Indication	Discovery agent		Investigative	[538787]
Structure		Download 2D MOL
Formula	C19H25F3N4O
InChI	InChI=1S/C19H25F3N4O/c1-14(24-11-10-17-12-23-13-25-17)4-2-3-5-18(27)26-16-8-6-15(7-9-16)19(20,21)22/h6-9,12-14,24H,2-5,10-11H2,1H3,(H,23,25)(H,26,27)
InChIKey	PMKJGGBYYNEYPA-UHFFFAOYSA-N
PubChem Compound ID	124846
PubChem Substance ID	4345729, 14804711, 15004238, 26751819, 29304795, 53439012, 53911441, 57309642, 57341085, 85230024, 85788608, 103259856, 104421786, 126435538, 128937063, 135081308, 135650354, 137128387, 139426851, 162222024, 179447910
Target and Pathway
Target(s)	Histamine H4 receptor	Target Info	Agonist	[525965]
KEGG Pathway	Neuroactive ligand-receptor interaction
Reactome	Histamine receptors
Reactome	G alpha (i) signalling events
WikiPathways	GPCR ligand binding
	GPCR downstream signaling
	GPCRs, Other
References
Ref 538787	(http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 1273).
Ref 525965	Cloning, expression, and pharmacological characterization of a novel human histamine receptor. Mol Pharmacol. 2001 Mar;59(3):434-41.

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Drug Information