Drug Information

Drug General Information
Drug ID
D09VYB
Former ID
DNC013135
Drug Name
UBP-302
Drug Type
Small molecular drug
Indication Discovery agent Investigative [467672]
Structure
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2D MOL

3D MOL
Formula
C15H15N3O6
InChI
InChI=1S/C15H15N3O6/c16-11(14(22)23)8-17-6-5-12(19)18(15(17)24)7-9-3-1-2-4-10(9)13(20)21/h1-6,11H,7-8,16H2,(H,20,21)(H,22,23)/t11-/m0/s1
InChIKey
UUIYULWYHDSXHL-NSHDSACASA-N
PubChem Compound ID
6420161
PubChem Substance ID
10322652, 11114273, 11618523, 16756377, 17137275, 43014341, 46394081, 53531461, 57366825, 91746442, 103473764, 104063523, 114518389, 134350340, 135698528, 162248777, 178101150, 228390411, 241375765, 252090112, 252156284
Target and Pathway
Target(s) Glutamate receptor, ionotropic kainate 1 Target Info Inhibitor [528453]
KEGG Pathway Neuroactive ligand-receptor interaction
Glutamatergic synapse
PANTHER Pathway Huntington disease
Ionotropic glutamate receptor pathway
Metabotropic glutamate receptor group III pathway
Metabotropic glutamate receptor group I pathway
WikiPathways Neurotransmitter Receptor Binding And Downstream Transmission In The Postsynaptic Cell
References
Ref 467672(http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 4333).
Ref 528453J Med Chem. 2006 Oct 5;49(20):6015-26.Structural investigation of the 7-chloro-3-hydroxy-1H-quinazoline-2,4-dione scaffold to obtain AMPA and kainate receptor selective antagonists. Synthesis, pharmacological, and molecular modeling studies.

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