Drug Information
| Drug General Information | |||||
|---|---|---|---|---|---|
| Drug ID |
D09XQU
|
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| Former ID |
DIB016952
|
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| Drug Name |
Tirapazamine
|
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| Synonyms |
TPZ; Tirazone; SR-259075; SR-4233; SR-4317; SR-4330; SR-4482; Win-59075
|
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| Drug Type |
Small molecular drug
|
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| Indication | Mild alzheimer disease [ICD9: 331; ICD10:G30] | Phase 3 | [1] | ||
| Company |
Sri international
|
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| Structure |
|
Download2D MOL |
|||
| Formula |
C7H6N4O2
|
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| Canonical SMILES |
[n+]1(nc([n+](c2c1cccc2)[O-])N)[O-]
|
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| CAS Number |
CAS 27314-97-2
|
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| PubChem Compound ID | |||||
| Target and Pathway | |||||
| Target(s) | DNA topoisomerase II | Target Info | Modulator | [2] | |
| References | |||||
| REF 1 | ClinicalTrials.gov (NCT00262821) Cisplatin and Radiation Therapy With or Without Tirapazamine in Treating Patients With Cervical Cancer. U.S. National Institutes of Health. | ||||
| REF 2 | Interpreting expression profiles of cancers by genome-wide survey of breadth of expression in normal tissues. Genomics 2005 Aug;86(2):127-41. | ||||
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