Drug Information
| Drug General Information | |||||
|---|---|---|---|---|---|
| Drug ID |
D09XUB
|
||||
| Former ID |
DCL000278
|
||||
| Drug Name |
Viramidine
|
||||
| Synonyms |
Ribamidine; Prodrug of Ribavirin; Ribavirin amidine; Taribavirin hydrochloride; ICN 3142; AVS-000206; AVS-206;ICN-3142; Taribavirin hydrochloride (USAN); Viramidine (TN); 1-.Beta.-D-Ribofuranosyl-1,2,4-triazole-3-carboximidine hydrochloride; 1-[(2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-1,2,4-triazole-3-carboximidamide; 1-[(2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-1,2,4-triazole-3-carboximidamide hydrochloride; 1-beta-D-Ribofuranosyl-1,2,4-triazole-3-carboximidine
|
||||
| Drug Type |
Small molecular drug
|
||||
| Indication | HCV infection [ICD9: 070.4, 070.5, 070.70; ICD10:B17.1, B18.2] | Phase 3 | [1] | ||
| Company |
Valeant Pharmaceuticals International
|
||||
| Structure |
|
Download2D MOL |
|||
| Formula |
C8H13N5O4
|
||||
| Canonical SMILES |
C1=NC(=NN1C2C(C(C(O2)CO)O)O)C(=N)N
|
||||
| InChI |
1S/C8H13N5O4/c9-6(10)7-11-2-13(12-7)8-5(16)4(15)3(1-14)17-8/h2-5,8,14-16H,1H2,(H3,9,10)/t3-,4-,5-,8-/m1/s1
|
||||
| InChIKey |
NHKZSTHOYNWEEZ-AFCXAGJDSA-N
|
||||
| CAS Number |
CAS 119567-79-2
|
||||
| PubChem Compound ID | |||||
| PubChem Substance ID | |||||
| Target and Pathway | |||||
| Target(s) | Inosine-5'-monophosphate dehydrogenase | Target Info | Inhibitor | [2] | |
| References | |||||
| REF 1 | A phase III study of the safety and efficacy of viramidine versus ribavirin in treatment-na?ve patients with chronic hepatitis C: ViSER1 results. Hepatology. 2009 Sep;50(3):717-26. | ||||
| REF 2 | Antiviral agents active against influenza A viruses. Nat Rev Drug Discov. 2006 Dec;5(12):1015-25. | ||||
If You Find Any Error in Data or Bug in Web Service, Please Kindly Report It to Dr. Zhou and Dr. Zhang.