Drug Information
| Drug General Information | |||||
|---|---|---|---|---|---|
| Drug ID |
D09YDM
|
||||
| Former ID |
DNC000385
|
||||
| Drug Name |
Camptothecin
|
||||
| Drug Type |
Small molecular drug
|
||||
| Indication | Solid tumours [ICD9: 140-199, 210-229; ICD10:C00-D48] | Phase 3 | [528447] | ||
| Structure |
|
Download2D MOL |
|||
| Formula |
C20H16N2O4
|
||||
| Canonical SMILES |
CCC1(C2=C(COC1=O)C(=O)N3CC4=CC5=CC=CC=C5N=C4C3=C2)O
|
||||
| InChI |
1S/C20H16N2O4/c1-2-20(25)14-8-16-17-12(7-11-5-3-4-6-15(11)21-17)9-22(16)18(23)13(14)10-26-19(20)24/h3-8,25H,2,9-10H2,1H3/t20-/m0/s1
|
||||
| InChIKey |
VSJKWCGYPAHWDS-FQEVSTJZSA-N
|
||||
| CAS Number |
CAS 2086-83-1
|
||||
| PubChem Compound ID | |||||
| PubChem Substance ID |
5009, 399733, 597746, 842008, 925175, 3140967, 7887296, 7978848, 8139651, 8150064, 8167780, 10321203, 11111011, 11112910, 11113913, 11120280, 11120768, 11121256, 11336001, 11341983, 11361240, 11362166, 11363193, 11365755, 11368317, 11372185, 11374175, 11376479, 11377982, 11446457, 11462212, 11466228, 11467348, 11484482, 11485816, 11487568, 11488719, 11491018, 11492553, 11494113, 11537709, 14827597, 14900711, 17404904, 24278352, 26612343, 26680346, 26732559, 26747153, 26747154
|
||||
| ChEBI ID |
ChEBI:16118
|
||||
| Drug Resistance Mutation (DRM) | |||||
| DRM | DRM Info | ||||
| Target and Pathway | |||||
| Target(s) | Toposisomerase-1 | Target Info | Modulator | [528447] | |
| NetPath Pathway | IL2 Signaling Pathway | ||||
| PANTHER Pathway | DNA replication | ||||
| Pathway Interaction Database | Caspase Cascade in Apoptosis | ||||
| WikiPathways | Integrated Pancreatic Cancer Pathway | ||||
| References | |||||
If You Find Any Error in Data or Bug in Web Service, Please Kindly Report It to Dr. Zhou and Dr. Zhang.