Drug Information
| Drug General Information | |||||
|---|---|---|---|---|---|
| Drug ID |
D0A1KR
|
||||
| Former ID |
DIB014655
|
||||
| Drug Name |
JTK-652
|
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| Synonyms |
HCV NS5B polymerase inhibitors (JTK-109 derivatives), Japan Tobacco; JTK-109 derivatives (HCV), Japan Tobacco
|
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| Indication | HCV infection [ICD9: 070.4, 070.5, 070.70; ICD10:B17.1, B18.2] | Discontinued in Phase 1 | [1] | ||
| Company |
Japan Tobacco Inc
|
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| Structure |
|
Download2D MOL |
|||
| Canonical SMILES |
C(=O)(O)c1cc2c(c(C3CCCCC3)c3n2CCOc2c3ccc(c2)OCc2ccccc2)<br />cc1
|
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| Target and Pathway | |||||
| Target(s) | Hepatitis C virus NS5B polymerase | Target Info | Inhibitor | [2] | |
| References | |||||
| REF 1 | Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800027431) | ||||
| REF 2 | Safety and antiviral activity of JTK-652: a novel HCV infection inhibitor. Antivir Ther. 2010;15(5):765-73. | ||||
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