Drug Information

Drug General Information
Drug ID
D0A6EE
Former ID
DPR000029
Drug Name
CHIR-01020
Drug Type
Small molecular drug
Indication Obesity [ICD9: 278; ICD10:E66] Preclinical [536122]
Company
Chiron; GSK
Structure
Download
2D MOL

3D MOL
Formula
C21H26BrNO4
Canonical SMILES
C[N+]1(CCC23C4C(=O)CCC2(C1CC5=C3C(=C(C=C5)O)O4)O)CC6CC6<br />.[Br-]
InChI
1S/C21H25NO4.BrH/c1-22(11-12-2-3-12)9-8-20-17-13-4-5-14(23)18(17)26-19(20)15(24)6-7-21(20,25)16(22)10-13;/h4-5,12,16,19,25H,2-3,6-11H2,1H3;1H/t16-,19+,20+,21-,22?;/m1./s1
InChIKey
IFGIYSGOEZJNBE-KNLJMPJLSA-N
CAS Number
CAS 83387-25-1
PubChem Compound ID
5361917
PubChem Substance ID
11653979, 14832534, 14905674, 39384348, 47208269, 49684206, 57362073, 80810136, 92251514, 103771498, 118844001, 126684693, 134339505, 135011307, 152035633, 164229822, 184811781, 223680086, 228875020, 252479732
SuperDrug ATC ID
N07BB04
SuperDrug CAS ID
cas=016590413
Target and Pathway
Target(s) Melanocortin-4 receptor Target Info Agonist [536122]
KEGG Pathway Neuroactive ligand-receptor interaction
Pathway Interaction Database Syndecan-3-mediated signaling events
Reactome Peptide ligand-binding receptors
G alpha (s) signalling events
WikiPathways GPCRs, Class A Rhodopsin-like
Peptide GPCRs
GPCR ligand binding
GPCR downstream signaling
References
Ref 536122Emerging drugs for obesity: linking novel biological mechanisms to pharmaceutical pipelines. Expert Opin Emerg Drugs. 2005 Aug;10(3):643-60.
Ref 536122Emerging drugs for obesity: linking novel biological mechanisms to pharmaceutical pipelines. Expert Opin Emerg Drugs. 2005 Aug;10(3):643-60.

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