Drug Information

Drug General Information
Drug ID
D0A6NQ
Former ID
DIB018788
Drug Name
AHPN
Synonyms
Ro 47-2077; 6-[3-(1-adamantyl)-4-hydroxyphenyl]-2-naphthalene carboxylic acid; CD437; CD 437
Drug Type
Small molecular drug
Indication Discovery agent Investigative [540373]
Structure
Download
2D MOL
Formula
C27H26O3
InChI
InChI=1S/C27H26O3/c28-25-6-5-22(20-1-2-21-11-23(26(29)30)4-3-19(21)10-20)12-24(25)27-13-16-7-17(14-27)9-18(8-16)15-27/h1-6,10-12,16-18,28H,7-9,13-15H2,(H,29,30)
InChIKey
LDGIHZJOIQSHPB-UHFFFAOYSA-N
PubChem Compound ID
135411
PubChem Substance ID
10243912, 14781189, 15328007, 15676134, 24724445, 26753174, 29312917, 49995528, 53788172, 57345179, 80475298, 85788664, 103344674, 103978817, 104384416, 124891579, 128472472, 135091121, 136368004, 136946597, 137163478, 140059764, 144115801, 162023153, 162248383, 162260503, 162312832, 163305694, 164839342, 172849980, 174006355, 178100433, 179149743, 204377885, 223704951, 226535571, 241182520, 241375492, 242059771, 249615587, 252215114, 252343221
Target and Pathway
Target(s) Retinoic acid receptor gamma Target Info Agonist [534078]
Reactome Nuclear Receptor transcription pathway
WikiPathways Vitamin A and Carotenoid Metabolism
Nuclear Receptors in Lipid Metabolism and Toxicity
Mesodermal Commitment Pathway
Endoderm Differentiation
Nuclear Receptors
References
Ref 540373(http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 3431).
Ref 534078Synthesis, structure-affinity relationships, and biological activities of ligands binding to retinoic acid receptor subtypes. J Med Chem. 1995 Dec 22;38(26):4993-5006.

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