Drug Information
| Drug General Information | |||||
|---|---|---|---|---|---|
| Drug ID |
D0A6YN
|
||||
| Former ID |
DIB016242
|
||||
| Drug Name |
SUN-C5174
|
||||
| Synonyms |
5-[3-[4-(4-Fluorophenyl)piperazin-1-yl]propyl]-8(S)-hydroxy-1-methyl-1,4,5,6,7,8-hexahydropyrrolo[3,2-c]azepin-4-one
|
||||
| Indication | Peripheral vascular disease [ICD9: 443.9; ICD10:I73.9] | Discontinued in Phase 2 | [1] | ||
| CAS Number |
CAS 191592-36-6
|
||||
| Target and Pathway | |||||
| Target(s) | 5-HT 2 receptor | Target Info | Antagonist | [2] | |
| KEGG Pathway | Calcium signaling pathway | ||||
| Neuroactive ligand-receptor interaction | |||||
| Gap junction | |||||
| Serotonergic synapse | |||||
| Inflammatory mediator regulation of TRP channels | |||||
| References | |||||
| REF 1 | Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800012828) | ||||
| REF 2 | Synthesis and serotonin 2 (5-HT2) receptor antagonist activity of 5-aminoalkyl-substituted pyrrolo[3,2-c]azepines and related compounds. Chem Pharm Bull (Tokyo). 2000 May;48(5):623-35. | ||||
If You Find Any Error in Data or Bug in Web Service, Please Kindly Report It to Dr. Zhou and Dr. Zhang.