Drug General Information
Drug ID	D0AL2E
Former ID	DNC006463
Drug Name	3-(pyridin-4-yl)-1H-indol-7-amine
Drug Type	Small molecular drug
Indication	Discovery agent		Investigative	[528040]
Structure		Download 2D MOL 3D MOL
Formula	C13H11N3
Canonical SMILES	C1=CC2=C(C(=C1)N)NC=C2C3=CC=NC=C3
InChI	1S/C13H11N3/c14-12-3-1-2-10-11(8-16-13(10)12)9-4-6-15-7-5-9/h1-8,16H,14H2
InChIKey	NVYSWJKBWRBXSR-UHFFFAOYSA-N
PubChem Compound ID	44410707
Target and Pathway
Target(s)	Inosine-5'-monophosphate dehydrogenase 2	Target Info	Inhibitor	[528040]
BioCyc Pathway	Purine nucleotides degradation
	Urate biosynthesis/inosine 5'-phosphate degradation
	Guanosine nucleotides de novo biosynthesis
	Superpathway of purine nucleotide salvage
	Purine nucleotides de novo biosynthesis
	Guanosine ribonucleotides de novo biosynthesis
KEGG Pathway	Purine metabolism
	Drug metabolism - other enzymes
	Metabolic pathways
PANTHER Pathway	De novo purine biosynthesis
Reactome	Purine ribonucleoside monophosphate biosynthesis
References
Ref 528040	Bioorg Med Chem Lett. 2006 May 1;16(9):2535-8. Epub 2006 Feb 17.Low molecular weight indole fragments as IMPDH inhibitors.
Ref 528040	Bioorg Med Chem Lett. 2006 May 1;16(9):2535-8. Epub 2006 Feb 17.Low molecular weight indole fragments as IMPDH inhibitors.

If You Find Any Error in Data or Bug in Web Service, Please Kindly Report It to Dr. Zhou and Dr. Zhang.