TTD | Drug: D0B0NQ

Drug General Information
Drug ID	D0B0NQ
Former ID	DCL001099
Drug Name	LY293558
Drug Type	Small molecular drug
Indication	Pain [ICD9: 338, 356.0, 356.8,780; ICD10:G64, G90.0, R52, G89]		Phase 2	[1], [2]
Therapeutic Class	Analgesics
Company	Eli Lilly
Structure		Download 2D MOL 3D MOL
Formula	C13H21N5O2
InChIKey	ZXFRFPSZAKNPQQ-YTWAJWBKSA-N
CAS Number	CAS 150131-78-5
PubChem Compound ID	127894
PubChem Substance ID	7979821, 14824420, 29307068, 49986466, 57342364, 75783333, 103177343, 103978702, 104366869, 129968233, 134223894, 134340739, 135082925, 136352800, 137237314, 140341563, 141003666, 152258903, 160647750, 163303823, 172919679, 178101062, 184812211, 196375798, 198985362, 227838645
Target and Pathway
Target(s)	Glutamate receptor, ionotropic kainate 1	Target Info	Modulator	[2]
KEGG Pathway	Neuroactive ligand-receptor interaction
KEGG Pathway	Glutamatergic synapse
PANTHER Pathway	Huntington disease
	Ionotropic glutamate receptor pathway
	Metabotropic glutamate receptor group III pathway
	Metabotropic glutamate receptor group I pathway
WikiPathways	Neurotransmitter Receptor Binding And Downstream Transmission In The Postsynaptic Cell
References
REF 1	(http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 4245).
REF 2	Pharmacogenetics of new analgesics. Br J Pharmacol. 2011 Jun;163(3):447-60.

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Drug Information