Drug Information

Drug General Information
Drug ID
D0B1DA
Former ID
DIB013067
Drug Name
SAND-5
Synonyms
Mubodina; Complement C5 minibody (hemolytic uremic syndrome/hemolytic uremic syndrome), ADIENNE
Indication Glomerulonephritis [ICD9: 580-582; ICD10:N00, N01, N03, N18] Preclinical [549143]
Company
ADIENNE Pharma & Biotech
Target and Pathway
Target(s) Complement C5 Target Info Inhibitor [544286]
KEGG Pathway Complement and coagulation cascades
Prion diseases
Pertussis
Staphylococcus aureus infection
Herpes simplex infection
Systemic lupus erythematosus
Reactome Activation of C3 and C5
Peptide ligand-binding receptors
G alpha (i) signalling events
Regulation of Complement cascade
WikiPathways Complement Activation, Classical Pathway
Human Complement System
Spinal Cord Injury
Allograft Rejection
GPCR ligand binding
GPCR downstream signaling
Complement cascade
References
Ref 549143Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800032848)
Ref 544286Progress and Trends in Complement Therapeutics. Adv Exp Med Biol. 2013; 734: 1-22.

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