Drug Information

Drug General Information
Drug ID
D0B2VW
Former ID
DNC013913
Drug Name
2S,4R-4-METHYLGLUTAMATE
Drug Type
Small molecular drug
Indication Discovery agent Investigative [529560]
Structure
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2D MOL

3D MOL
Formula
C6H11NO4
Canonical SMILES
CC(CC(C(=O)O)N)C(=O)O
InChI
1S/C6H11NO4/c1-3(5(8)9)2-4(7)6(10)11/h3-4H,2,7H2,1H3,(H,8,9)(H,10,11)/t3-,4+/m1/s1
InChIKey
KRKRAOXTGDJWNI-DMTCNVIQSA-N
PubChem Compound ID
95883
Target and Pathway
Target(s) Metabotropic glutamate receptor Target Info Inhibitor [530441]
Glutamate receptor, ionotropic kainate 1 Target Info Inhibitor [529560]
KEGG Pathway Neuroactive ligand-receptor interaction
Glutamatergic synapse
PANTHER Pathway Huntington disease
Ionotropic glutamate receptor pathway
Metabotropic glutamate receptor group III pathway
Metabotropic glutamate receptor group I pathway
WikiPathways Neurotransmitter Receptor Binding And Downstream Transmission In The Postsynaptic Cell
References
Ref 529560J Med Chem. 2008 Jul 24;51(14):4093-103. Epub 2008 Jun 25.Chemo-enzymatic synthesis of a series of 2,4-syn-functionalized (S)-glutamate analogues: new insight into the structure-activity relation ofionotropic glutamate receptor subtypes 5, 6, and 7.
Ref 529560J Med Chem. 2008 Jul 24;51(14):4093-103. Epub 2008 Jun 25.Chemo-enzymatic synthesis of a series of 2,4-syn-functionalized (S)-glutamate analogues: new insight into the structure-activity relation ofionotropic glutamate receptor subtypes 5, 6, and 7.
Ref 530441Eur J Med Chem. 2010 Jan;45(1):69-77. Epub 2009 Sep 16.Substituted 2-aminothiopen-derivatives: a potential new class of GluR6-antagonists.

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