Drug Information

Drug General Information
Drug ID
D0B4DC
Former ID
DAP001236
Drug Name
Butenafine
Synonyms
Butenafina; Butenafinum; Mentax; Butenafine HCL; Butenafine [INN]; Butenafine hydrochloride; KP 363; Butenafina [INN-Spanish]; Butenafine (INN); Butenafinum [INN-Latin]; Butop (TN); KP-363; Mentax (TN); N-4-tert-butylbenzyl-N-methyl-1-naphthalene methylamine hydrochloride; N-p-tert-Butylbenzyl-N-methyl-1-naphthalenemethylamine; N-(p-tert-Butylbenzyl)-N-methyl-1-naphthalenemethylamine; 1-(4-tert-butylphenyl)-N-methyl-N-(naphthalen-1-ylmethyl)methanamine; 4-tert-butylbenzyl(methyl)(1-naphthalenemethyl)amine
Drug Type
Small molecular drug
Indication Dermatologic infections [ICD9: 680-686; ICD10:L00-L08] Approved [536361]
Therapeutic Class
Antifungal Agents
Company
Schering-Plough
Structure
Download
2D MOL

3D MOL
Formula
C23H27N
Canonical SMILES
CC(C)(C)C1=CC=C(C=C1)CN(C)CC2=CC=CC3=CC=CC=C32
InChI
1S/C23H27N/c1-23(2,3)21-14-12-18(13-15-21)16-24(4)17-20-10-7-9-19-8-5-6-11-22(19)20/h5-15H,16-17H2,1-4H3
InChIKey
ABJKWBDEJIDSJZ-UHFFFAOYSA-N
CAS Number
CAS 101828-21-1
PubChem Compound ID
2484
PubChem Substance ID
10267, 603409, 5615389, 8151659, 11342191, 11362374, 11364447, 11367009, 11369571, 11377733, 11487776, 11495367, 14874583, 29215487, 29215488, 29221648, 46506191, 50064067, 51091907, 56313731, 57321348, 79503477, 81040926, 89736078, 92308960, 92712424, 92729938, 93166394, 103261258, 104300725, 124766539, 125336650, 126630107, 126683136, 127381627, 134338475, 135023666, 137006422, 142244396, 144205282, 152034324, 160964425, 162177723, 162201865, 163123303, 164814813, 170465093, 175268882, 175449030, 176484075
SuperDrug ATC ID
D01AE23
SuperDrug CAS ID
cas=101828211
Target and Pathway
Target(s) Fungal squalene epoxidase Target Info Modulator [556264]
References
Ref 536361Natural products as sources of new drugs over the last 25 years. J Nat Prod. 2007 Mar;70(3):461-77. Epub 2007 Feb 20.
Ref 556264Drugs@FDA. U.S. Food and Drug Administration. U.S. Department of Health & Human Services.

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