Drug General Information
Drug ID	D0B4WR
Former ID	DNC012031
Drug Name	2-Isoxazol-5-yl-3H-imidazo[4,5-c]quinoline
Drug Type	Small molecular drug
Indication	Discovery agent		Investigative	[534155]
Structure		Download 2D MOL 3D MOL
Formula	C13H8N4O
Canonical SMILES	C1=CC=C2C(=C1)C3=NC(=C4C=CNO4)N=C3C=N2
InChI	1S/C13H8N4O/c1-2-4-9-8(3-1)12-10(7-14-9)16-13(17-12)11-5-6-15-18-11/h1-7,15H/b13-11-
InChIKey	DUIZUGINLYIMFH-QBFSEMIESA-N
PubChem Compound ID	10513958
Target and Pathway
Target(s)	Gamma-aminobutyric acid receptor subunit alpha-1	Target Info	Inhibitor	[534155]
	Gamma-aminobutyric acid receptor subunit beta-2	Target Info	Inhibitor	[534155]
	Gamma-aminobutyric acid receptor subunit gamma-2	Target Info	Inhibitor	[534155]
	Gamma-aminobutyric acid receptor	Target Info	Inhibitor	[534155]
KEGG Pathway	Neuroactive ligand-receptor interaction
	Retrograde endocannabinoid signaling
	GABAergic synapse
	Morphine addiction
	Nicotine addictionhsa04080:Neuroactive ligand-receptor interaction
	Serotonergic synapse
	Nicotine addiction
Reactome	Ligand-gated ion channel transport
	GABA A receptor activationR-HSA-975298:Ligand-gated ion channel transport
	GABA A receptor activation
WikiPathways	SIDS Susceptibility Pathways
	Neurotransmitter Receptor Binding And Downstream Transmission In The Postsynaptic Cell
	Iron uptake and transportWP2754:Neurotransmitter Receptor Binding And Downstream Transmission In The Postsynaptic Cell
	Iron uptake and transport
References
Ref 534155	J Med Chem. 1996 Jul 5;39(14):2844-51.Synthesis and structure--activity relationships of fused imidazopyridines: a new series of benzodiazepine receptor ligands.
Ref 534155	J Med Chem. 1996 Jul 5;39(14):2844-51.Synthesis and structure--activity relationships of fused imidazopyridines: a new series of benzodiazepine receptor ligands.

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