TTD | Drug: D0B5ST

Drug General Information
Drug ID	D0B5ST
Former ID	DNC014198
Drug Name	2-(3-Bromophenylthio)-N,N-dimethylethanamine
Drug Type	Small molecular drug
Indication	Discovery agent		Investigative	[530699]
Structure		Download 2D MOL 3D MOL
Formula	C10H14BrNS
Canonical SMILES	CN(C)CCSC1=CC(=CC=C1)Br
InChI	1S/C10H14BrNS/c1-12(2)6-7-13-10-5-3-4-9(11)8-10/h3-5,8H,6-7H2,1-2H3
InChIKey	LIEFSMJAVJRLBQ-UHFFFAOYSA-N
PubChem Compound ID	46233484
Target and Pathway
Target(s)	5-hydroxytryptamine 1A receptor	Target Info	Inhibitor	[530699]
KEGG Pathway	cAMP signaling pathway
	Neuroactive ligand-receptor interaction
	Serotonergic synapse
PANTHER Pathway	Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway
PANTHER Pathway	5HT1 type receptor mediated signaling pathway
Reactome	Serotonin receptors
Reactome	G alpha (i) signalling events
WikiPathways	Serotonin HTR1 Group and FOS Pathway
	SIDS Susceptibility Pathways
	Monoamine GPCRs
	GPCRs, Class A Rhodopsin-like
	GPCR ligand binding
	GPCR downstream signaling
References
Ref 530699	Bioorg Med Chem. 2010 Mar 1;18(5):1958-67. Epub 2010 Jan 18.SAR studies on new bis-aryls 5-HT7 ligands: Synthesis and molecular modeling.
Ref 530699	Bioorg Med Chem. 2010 Mar 1;18(5):1958-67. Epub 2010 Jan 18.SAR studies on new bis-aryls 5-HT7 ligands: Synthesis and molecular modeling.

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Drug Information