Drug Information

Drug General Information
Drug ID
D0B8GN
Former ID
DIB005318
Drug Name
TM-30089
Synonyms
TM-30089; TM-30642; TM-30643; CRTH2 antagonists (asthma/allergy); CRTH2 antagonists, Ortho-McNeil; N(alpha)-tosyltryptophan; CRTH2 antagonists (asthma/allergy), 7TM/Ortho-McNeil
Indication Allergy [ICD9: 995.3; ICD10:T78.4] Investigative [543776]
Company
7TM Pharma A/S
Structure
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2D MOL

3D MOL
Canonical SMILES
c1ccc2c(c1)c1c(n2CC(=O)O)CCC(C1)N(S(=O)(=O)c1ccc(cc1)F)<br />C
Target and Pathway
Target(s) Putative G-protein coupled receptor 44 Target Info Antagonist [543776]
Reactome Prostanoid ligand receptors
G alpha (i) signalling events
WikiPathways GPCRs, Class A Rhodopsin-like
GPCR ligand binding
GPCR downstream signaling
References
Ref 543776(http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Target id: 339).
Ref 543776(http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Target id: 339).

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