Drug Information

Drug General Information
Drug ID
D0B8PD
Former ID
DIB018672
Drug Name
6-Cl-MLT
Synonyms
6-Cl-melatonin; 6-chloromelatonin
Drug Type
Small molecular drug
Indication Discovery agent Investigative [538823]
Structure
Download
2D MOL
Formula
C13H15ClN2O2
InChI
InChI=1S/C13H15ClN2O2/c1-8(17)15-4-3-9-7-16-12-6-11(14)13(18-2)5-10(9)12/h5-7,16H,3-4H2,1-2H3,(H,15,17)
InChIKey
LUINDDOUWHRIPW-UHFFFAOYSA-N
PubChem Compound ID
1858
PubChem Substance ID
6755088, 8151314, 11110901, 11113504, 15491087, 17404741, 26751723, 29221055, 47291320, 47515528, 47589183, 49858543, 50104413, 50104414, 53777284, 56463294, 57321048, 75272297, 85084766, 85208929, 85230954, 85788599, 90341286, 92303628, 92474752, 103206438, 103837837, 103974758, 104298926, 117460165, 121360881, 124749516, 124800835, 124879534, 124879535, 124879536, 125666026, 128542708, 135077116, 135649846, 135698046, 137242479, 137242480, 162022438, 162092102, 163132019, 163564132, 178127342, 179235698, 184589682
Target and Pathway
Target(s) Melatonin receptor Target Info Agonist [533401]
KEGG Pathway Neuroactive ligand-receptor interaction
Circadian entrainment
Reactome Class A/1 (Rhodopsin-like receptors)
G alpha (i) signalling events
WikiPathways GPCRs, Class A Rhodopsin-like
Small Ligand GPCRs
GPCR ligand binding
GPCR downstream signaling
References
Ref 538823(http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 1346).
Ref 533401Characterization of a retinal melatonin receptor. J Pharmacol Exp Ther. 1985 Aug;234(2):395-401.

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