Drug Information

Drug General Information
Drug ID
D0BG5H
Former ID
DNC001292
Drug Name
SB 269970-A
Drug Type
Small molecular drug
Indication Discovery agent Investigative [535905]
Structure
Download
2D MOL

3D MOL
Formula
C18H29ClN2O3S
Canonical SMILES
CC1CCN(CC1)CCC2CCCN2S(=O)(=O)C3=CC=CC(=C3)O.Cl
InChI
1S/C18H28N2O3S.ClH/c1-15-7-11-19(12-8-15)13-9-16-4-3-10-20(16)24(22,23)18-6-2-5-17(21)14-18;/h2,5-6,14-16,21H,3-4,7-13H2,1H3;1H/t16-;/m1./s1
InChIKey
XQCJOYZLWFNDIO-PKLMIRHRSA-N
CAS Number
CAS 65057-90-1
PubChem Compound ID
11957684
PubChem Substance ID
17405615, 23919085, 24260372, 24278708, 36454947, 50106961, 52386671, 53778165, 56463268, 57377673, 91722372, 92303336, 123096079, 135698456, 152344057, 160830073, 162009752, 162249252, 163094384, 163394396, 163565013, 163843258, 170485746, 172821418, 175612661, 204431377, 210275224, 210280863, 228805463, 241182573, 252160802, 252470807
Target and Pathway
Target(s) 5-hydroxytryptamine 7 receptor Target Info Antagonist [535905]
KEGG Pathway Ras signaling pathway
Calcium signaling pathway
Neuroactive ligand-receptor interaction
Serotonergic synapse
PANTHER Pathway Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway
PathWhiz Pathway Excitatory Neural Signalling Through 5-HTR 7 and Serotonin
Reactome Serotonin receptors
G alpha (s) signalling events
WikiPathways Serotonin Receptor 4/6/7 and NR3C Signaling
Monoamine GPCRs
GPCRs, Class A Rhodopsin-like
GPCR ligand binding
GPCR downstream signaling
GPCRs, Other
References
Ref 5359055-HT7 receptors. Curr Drug Targets CNS Neurol Disord. 2004 Feb;3(1):81-90.
Ref 5359055-HT7 receptors. Curr Drug Targets CNS Neurol Disord. 2004 Feb;3(1):81-90.

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