Drug General Information
Drug ID	D0BN7E
Former ID	DNC007848
Drug Name	5-isopropyl-2-(phenylamino)thiazol-4(5H)-one
Drug Type	Small molecular drug
Indication	Discovery agent		Investigative	[529083]
Structure		Download 2D MOL 3D MOL
Formula	C12H14N2OS
Canonical SMILES	CC(C)C1C(=O)N=C(S1)NC2=CC=CC=C2
InChI	1S/C12H14N2OS/c1-8(2)10-11(15)14-12(16-10)13-9-6-4-3-5-7-9/h3-8,10H,1-2H3,(H,13,14,15)
InChIKey	XLFDGKZAEMQJBH-UHFFFAOYSA-N
PubChem Compound ID	11608346
Target and Pathway
Target(s)	Corticosteroid 11-beta-dehydrogenase, isozyme 1	Target Info	Inhibitor	[529083]
KEGG Pathway	Steroid hormone biosynthesis
	Metabolism of xenobiotics by cytochrome P450
	Metabolic pathways
	Chemical carcinogenesis
NetPath Pathway	IL1 Signaling Pathway
	FSH Signaling Pathway
PathWhiz Pathway	Steroidogenesis
Reactome	Glucocorticoid biosynthesis
WikiPathways	Prostaglandin Synthesis and Regulation
	Metabolism of steroid hormones and vitamin D
	Glucocorticoid & Mineralcorticoid Metabolism
References
Ref 529083	Bioorg Med Chem Lett. 2007 Nov 15;17(22):6056-61. Epub 2007 Sep 25.The discovery of 2-anilinothiazolones as 11beta-HSD1 inhibitors.
Ref 529083	Bioorg Med Chem Lett. 2007 Nov 15;17(22):6056-61. Epub 2007 Sep 25.The discovery of 2-anilinothiazolones as 11beta-HSD1 inhibitors.

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