Drug Information
| Drug General Information | |||||
|---|---|---|---|---|---|
| Drug ID |
D0BR7M
|
||||
| Former ID |
DIB014953
|
||||
| Drug Name |
Breceptin
|
||||
| Synonyms |
B-10206; B-10396; B-10410; B-10458; B-199; B-201; B-201 acetate; B-202; B-9340; B-9430; B-9698; B-9870; CU-202; CU-201, Apoplogic
|
||||
| Indication | Cancer [ICD9: 140-229; ICD10:C00-C96] | Investigative | [541658] | ||
| Company |
University of Colorado System
|
||||
| Structure |
|
Download2D MOL |
|||
| Canonical SMILES |
N1(C(=O)[C@H](NC(=O)[C@@H](NC(=O)[C@H](C2Cc3c(C2)cccc3)<br />NC(=O)CNC(=O)[C@H]2N(C(=O)[C@H]3N(C(=O)[C@@H](NC(=O)[C@<br />H](NC(=N)CCCCCCC(=N)N[C@@H](C(=O)N[C@H](C(=O)N4[C@H](C(<br />=O)N5[C@H](C(=O)NCC(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@@H](<br />C(=O)N6[C@H](C(=O)N[C@H](C(=O)O)CCCNC(=N)N)C[C@H]7[C@@H<br />]6CCCC7)C6Cc7c(C6)cccc7)CO)C6Cc7c(C6)cccc7)C[C@H](C5)O)<br />CCC4)CCCNC(=N)N)CCCNC(=N)N)CCCNC(=N)N)CCCNC(=N)N)CCC3)C<br />[C@@H](C2)O)CO)C2Cc3c(C2)cccc3)[C@H](C(=O)N[C@H](C(=O)O<br />)CCCNC(=N)N)C[C@H]2[C@@H]1CCCC2
|
||||
| Target and Pathway | |||||
| Target(s) | B2 bradykinin receptor | Target Info | Modulator | [543819] | |
| KEGG Pathway | Calcium signaling pathway | ||||
| cGMP-PKG signaling pathway | |||||
| Sphingolipid signaling pathway | |||||
| Neuroactive ligand-receptor interaction | |||||
| Complement and coagulation cascades | |||||
| Inflammatory mediator regulation of TRP channels | |||||
| Regulation of actin cytoskeleton | |||||
| Endocrine and other factor-regulated calcium reabsorption | |||||
| Chagas disease (American trypanosomiasis) | |||||
| Pathways in cancer | |||||
| NetPath Pathway | TGF_beta_Receptor Signaling Pathway | ||||
| Pathway Interaction Database | Direct p53 effectors | ||||
| Validated transcriptional targets of deltaNp63 isoforms | |||||
| References | |||||
If You Find Any Error in Data or Bug in Web Service, Please Kindly Report It to Dr. Zhou and Dr. Zhang.