Drug Information
Drug General Information | |||||
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Drug ID |
D0C7JT
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Former ID |
DIB008134
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Drug Name |
YM-976
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Synonyms |
4-(3-Chlorophenyl)-1,7-diethylpyrido[2,3-d]pyrimidin-2(1H)-one
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Drug Type |
Small molecular drug
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Structure |
Download2D MOL |
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Formula |
C17H16ClN3O
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InChI |
InChI=1S/C17H16ClN3O/c1-3-13-8-9-14-15(11-6-5-7-12(18)10-11)20-17(22)21(4-2)16(14)19-13/h5-10H,3-4H2,1-2H3
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InChIKey |
MNHXYNNKDDXKNP-UHFFFAOYSA-N
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PubChem Compound ID | |||||
PubChem Substance ID |
11114229, 11646546, 14825817, 24724671, 43224654, 50035123, 57371147, 77248208, 85789052, 90341065, 91723004, 114638231, 121360857, 124974129, 128620489, 135698467, 137032995, 140275277, 162023248, 162248250, 162808926, 163563970, 172840200, 175612235, 178101975, 184598515, 204356757, 223454724, 225076537, 226521177, 241375634, 252156125
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Target and Pathway | |||||
Target(s) | Type IV phosphodiesterase | Target Info | Inhibitor | [551871] | |
CAMP-specific 3',5'-cyclic phosphodiesterase 4B | Target Info | Inhibitor | [531635] | ||
CAMP-specific 3',5'-cyclic phosphodiesterase 4A | Target Info | Inhibitor | [526009] | ||
NetPath Pathway | IL5 Signaling Pathway | ||||
IL2 Signaling Pathway | |||||
PathWhiz Pathway | Purine Metabolism | ||||
References | |||||
Ref 540755 | (http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 5292). | ||||
Ref 546870 | Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800010783) | ||||
Ref 526009 | Antiasthmatic effect of YM976, a novel PDE4 inhibitor, in guinea pigs. J Pharmacol Exp Ther. 2001 Apr;297(1):165-73. | ||||
Ref 531635 | Therapeutic target database update 2012: a resource for facilitating target-oriented drug discovery. Nucleic Acids Res. 2012 Jan;40(Database issue):D1128-36. | ||||
Ref 551871 | Drugs@FDA. U.S. Food and Drug Administration. U.S. Department of Health & Human Services. 2015 |
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