Drug Information

Drug General Information
Drug ID
D0C9TZ
Former ID
DNC012124
Drug Name
3-(3-Methanesulfonyl-phenyl)-1-propyl-pyrrolidine
Drug Type
Small molecular drug
Indication Discovery agent Investigative [551334]
Structure
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2D MOL

3D MOL
Formula
C14H21NO2S
Canonical SMILES
CCCN1CCC(C1)C2=CC(=CC=C2)S(=O)(=O)C
InChI
1S/C14H21NO2S/c1-3-8-15-9-7-13(11-15)12-5-4-6-14(10-12)18(2,16)17/h4-6,10,13H,3,7-9,11H2,1-2H3
InChIKey
RJYDYJIGFDPBRL-UHFFFAOYSA-N
PubChem Compound ID
44461148
Target and Pathway
Target(s) 5-hydroxytryptamine 1A receptor Target Info Inhibitor [551334]
KEGG Pathway cAMP signaling pathway
Neuroactive ligand-receptor interaction
Serotonergic synapse
PANTHER Pathway Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway
5HT1 type receptor mediated signaling pathway
Reactome Serotonin receptors
G alpha (i) signalling events
WikiPathways Serotonin HTR1 Group and FOS Pathway
SIDS Susceptibility Pathways
Monoamine GPCRs
GPCRs, Class A Rhodopsin-like
GPCR ligand binding
GPCR downstream signaling
References
Ref 551334Regioselective synthesis of 3-aryl substituted pyrrolidines via palladium catalyzed arylation: pharmacological evaluation for central dopaminergic and serotonergic activity, Bioorg. Med. Chem. Lett. 7(3):241-246 (1997).
Ref 551334Regioselective synthesis of 3-aryl substituted pyrrolidines via palladium catalyzed arylation: pharmacological evaluation for central dopaminergic and serotonergic activity, Bioorg. Med. Chem. Lett. 7(3):241-246 (1997).

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