Drug Information
Drug General Information | |||||
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Drug ID |
D0CP4E
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Former ID |
DAP000259
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Drug Name |
Clonazepam
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Synonyms |
Antelepsin; Antilepsin; Chlonazepam; Cloazepam; Clonazepamum; Clonex; Clonopin; Iktorivil; Kenoket; Klonopin; Landsen; Lktorivil; Lonazep; Melzap; Paxam; Ravotril; Rivatril; Rivoril; Rivotril; Solfidin; Klonopin Rapidly Disintegrating; DF2374250; RO4023; Ro 4023; Ro 54023; Alti-Clonazepam; Clonazepamum [INN-Latin]; Klonopin (TN); Ravotril (TN); Rivatril (TN); Rivotril (TN); Ro 4-8180; Ro 5-4023; Ro-5-4023; Clonazepam (JP15/USP/INN); Clonazepam [USAN:INN:BAN:JAN]; Ro 5-4023/B-7; 1,3-Dihydro-5-(o-chlorophenyl)-7-nitro-3H-1,4-benzodiazepin-2-one; 1,3-Dihydro-7-nitro-5-(2-chlorophenyl)-2H-1,4.benzodiazepin-2-one; 5-(2-Chloro-phenyl)-7-nitro-1,3-dihydro-benzo[e][1,4]diazepin-2-one; 5-(2-Chlorophenyl)-1,3-dihydro-7-nitro-2H-1,4-benzodiazepin-2-one; 5-(2-Chlorophenyl)-7-nitro-1,3-dihydro-2H-1,4-benzodiazepin-2-one; 5-(2-Chlorophenyl)-7-nitro-3H-1,4-benzodiazepin-2(1H)-one; 5-(2-chlorophenyl)-7-nitro-1,3-dihydro-1,4-benzodiazepin-2-one; 5-(o-Chlorophenyl)-1,3-dihydro-7-nitro-2H-1,4-benzodiazepin-2-one; 5-(o-Chlorophenyl)-7-nitro-1H-1,4-benzodiazepin-2(3H)-one; 5-(o-chlorophenyl)-7-nitro-1,3-dihydro-2H-1,4-benzodiazepin-2-one; 7-Nitro-5-(2-chlorophenyl)-3H-1,4-benzodiazepin-2(1H)-one
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Drug Type |
Small molecular drug
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Therapeutic Class |
Anticonvulsants
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Company |
Roche Pharmaceuticals
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Structure |
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Download2D MOL |
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Formula |
C15H10ClN3O3
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InChI |
InChI=1S/C15H10ClN3O3/c16-12-4-2-1-3-10(12)15-11-7-9(19(21)22)5-6-13(11)18-14(20)8-17-15/h1-7H,8H2,(H,18,20)
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InChIKey |
DGBIGWXXNGSACT-UHFFFAOYSA-N
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CAS Number |
CAS 1622-61-3
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PubChem Compound ID | |||||
PubChem Substance ID |
447045, 629452, 4807399, 6242864, 7847346, 7978973, 8150128, 8151811, 10503355, 10509779, 10589180, 11109648, 11336148, 11361387, 11462359, 12146087, 14874486, 24892396, 29221957, 46507677, 47702094, 47736576, 48415805, 49884102, 49884205, 50876639, 56313737, 57321471, 85176029, 92307992, 92714482, 92729733, 93167162, 96026525, 96079552, 99302061, 103165964, 103930203, 104301655, 125536639, 126624103, 126655374, 126691438, 127729747, 131300953, 134337573, 134979678, 135315111, 136949632, 137002943
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SuperDrug ATC ID |
N03AE01
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SuperDrug CAS ID |
cas=001622613
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Target and Pathway | |||||
Target(s) | Gamma-aminobutyric acid receptor | Target Info | Agonist | [535248], [536166] | |
References | |||||
Ref 529439 | Residual effect of a 7-amino metabolite of clonazepam on GABAA receptor function in the nucleus reticularis thalami of the rat. Epilepsia. 2008 Oct;49(10):1803-8. | ||||
Ref 534170 | Characterization of GABAA receptor function in human temporal cortical neurons. J Neurophysiol. 1996 Apr;75(4):1458-71. | ||||
Ref 538277 | FDA Approved Drug Products from FDA Official Website. 2009. Application Number: (ANDA) 074569. | ||||
Ref 541998 | (http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 6963). |
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