Drug Information

Drug General Information
Drug ID
D0D2YZ
Former ID
DIB005032
Drug Name
BMTP-11
Synonyms
IL-11Ralpha targeted proapoptotic peptide (prostate cancer), MD Anderson Cancer Center; IL-11Ralpha targeted proapoptotic peptide (prostate cancer), Mercator
Indication Prostate cancer [ICD9: 185; ICD10:C61] Phase 1 [522624]
Company
MD Anderson Cancer Center
Target and Pathway
Target(s) Interleukin-11 receptor alpha chain Target Info Modulator [533180]
KEGG Pathway Cytokine-cytokine receptor interaction
Jak-STAT signaling pathway
Hematopoietic cell lineage
PANTHER Pathway Interleukin signaling pathway
WikiPathways Interleukin-11 Signaling Pathway
References
Ref 522624ClinicalTrials.gov (NCT00872157) BMTP-11 in Patients With Castrate-Resistant Prostate Cancer With Bone Mets. U.S. National Institutes of Health.
Ref 533180Targeting IL11 Receptor in Leukemia and Lymphoma: A Functional Ligand-Directed Study and Hematopathology Analysis of Patient-Derived Specimens. Clin Cancer Res. 2015 Jul 1;21(13):3041-51.

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