Drug Information

Drug General Information
Drug ID
D0D6IU
Former ID
DNC012597
Drug Name
2-(1H-Indol-3-yl)-2-oxo-N-phenethyl-acetamide
Drug Type
Small molecular drug
Indication Discovery agent Investigative [526738]
Structure
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2D MOL

3D MOL
Formula
C18H16N2O2
Canonical SMILES
C1=CC=C(C=C1)CCNC(=O)C(=O)C2=CNC3=CC=CC=C32
InChI
1S/C18H16N2O2/c21-17(15-12-20-16-9-5-4-8-14(15)16)18(22)19-11-10-13-6-2-1-3-7-13/h1-9,12,20H,10-11H2,(H,19,22)
InChIKey
USGVPHMVQJFJJD-UHFFFAOYSA-N
PubChem Compound ID
2176767
Target and Pathway
Target(s) Gamma-aminobutyric acid receptor subunit gamma-2 Target Info Inhibitor [526738]
Gamma-aminobutyric acid receptor Target Info Inhibitor [526738]
Gamma-aminobutyric acid receptor subunit alpha-1 Target Info Inhibitor [526738]
KEGG Pathway Neuroactive ligand-receptor interaction
Retrograde endocannabinoid signaling
GABAergic synapse
Morphine addiction
Nicotine addictionhsa04080:Neuroactive ligand-receptor interaction
Nicotine addiction
Reactome Ligand-gated ion channel transport
GABA A receptor activationR-HSA-975298:Ligand-gated ion channel transport
GABA A receptor activation
WikiPathways Neurotransmitter Receptor Binding And Downstream Transmission In The Postsynaptic Cell
Iron uptake and transportWP706:SIDS Susceptibility Pathways
Iron uptake and transport
References
Ref 526738J Med Chem. 1992 Jun 12;35(12):2214-20.Benzodiazepine receptor affinity and interaction of some N-(indol-3-ylglyoxylyl)amine derivatives.
Ref 526738J Med Chem. 1992 Jun 12;35(12):2214-20.Benzodiazepine receptor affinity and interaction of some N-(indol-3-ylglyoxylyl)amine derivatives.

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