Drug Information

Drug General Information
Drug ID
D0D7OR
Former ID
DNC009198
Drug Name
KM-233-M
Drug Type
Small molecular drug
Indication Discovery agent Investigative [529515]
Structure
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2D MOL

3D MOL
Formula
C25H29FO2
Canonical SMILES
CC1=CCC2C(C1)C3=C(C=C(C=C3O)C(C)(C)C4=CC(=CC=C4)F)OC2(C<br />)C
InChI
1S/C25H29FO2/c1-15-9-10-20-19(11-15)23-21(27)13-17(14-22(23)28-25(20,4)5)24(2,3)16-7-6-8-18(26)12-16/h6-9,12-14,19-20,27H,10-11H2,1-5H3/t19-,20-/m1/s1
InChIKey
IKKCHJJZMJZQEO-WOJBJXKFSA-N
PubChem Compound ID
44593431
Target and Pathway
Target(s) Cannabinoid receptor 1 Target Info Inhibitor [529515]
Cannabinoid receptor 2 Target Info Inhibitor [529515]
KEGG Pathway Rap1 signaling pathway
Neuroactive ligand-receptor interaction
Retrograde endocannabinoid signalinghsa04080:Neuroactive ligand-receptor interaction
PANTHER Pathway Endogenous cannabinoid signaling
Pathway Interaction Database N-cadherin signaling events
Reactome Class A/1 (Rhodopsin-like receptors)
G alpha (i) signalling eventsR-HSA-373076:Class A/1 (Rhodopsin-like receptors)
G alpha (i) signalling events
WikiPathways GPCRs, Class A Rhodopsin-like
Small Ligand GPCRs
BDNF signaling pathway
GPCR ligand binding
GPCR downstream signaling
GPCRs, OtherWP455:GPCRs, Class A Rhodopsin-like
References
Ref 529515Bioorg Med Chem. 2008 Jul 1;16(13):6489-500. Epub 2008 May 20.Exploring the substituent effects on a novel series of C1'-dimethyl-aryl Delta8-tetrahydrocannabinol analogs.
Ref 529515Bioorg Med Chem. 2008 Jul 1;16(13):6489-500. Epub 2008 May 20.Exploring the substituent effects on a novel series of C1'-dimethyl-aryl Delta8-tetrahydrocannabinol analogs.

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