Drug Information
Drug General Information | |||||
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Drug ID |
D0D7XW
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Former ID |
DIB000927
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Drug Name |
SINITRODIL
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Synonyms |
ITF-296; Sinitrodil < Prop INN >; 3-[2-(Nitrooxy)ethyl]-2H-1,3-benzoxazin-4(3H)-one
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Drug Type |
Small molecular drug
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Indication | Angina pectoris [ICD9: 413; ICD10:I20] | Discontinued in Phase 2 | [545952] | ||
Structure |
Download2D MOL |
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Formula |
C10H10N2O5
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Canonical SMILES |
[O-][N+](=O)OCCN1COc2ccccc2C1=O
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InChI |
1S/C10H10N2O5/c13-10-8-3-1-2-4-9(8)16-7-11(10)5-6-17-12(14)15/h1-4H,5-7H2
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InChIKey |
POVFCWQCRHXYAB-UHFFFAOYSA-N
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CAS Number |
CAS 143248-63-9
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PubChem Compound ID | |||||
Target and Pathway | |||||
Target(s) | CGMP-specific 3',5'-cyclic phosphodiesterase | Target Info | Modulator | [551871] | |
KEGG Pathway | Purine metabolism | ||||
cGMP-PKG signaling pathway | |||||
NetPath Pathway | TGF_beta_Receptor Signaling Pathway | ||||
Reactome | cGMP effects | ||||
References |
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