Drug General Information
Drug ID
D0E0GW
Former ID
DIB005064
Drug Name
BVT-3498
Synonyms
AMG-311
Indication Metabolic disorders [ICD9: 270-279; ICD10:E70-E89] Terminated [531312]
Company
Swedish Orphan Biovitrum AB
Structure
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2D MOL

3D MOL

Target and Pathway
Target(s) Corticosteroid 11-beta-dehydrogenase, isozyme 1 Target Info Inhibitor [531312]
KEGG Pathway Steroid hormone biosynthesis
Metabolism of xenobiotics by cytochrome P450
Metabolic pathways
Chemical carcinogenesis
NetPath Pathway IL1 Signaling Pathway
FSH Signaling Pathway
PathWhiz Pathway Steroidogenesis
Reactome Glucocorticoid biosynthesis
WikiPathways Prostaglandin Synthesis and Regulation
Metabolism of steroid hormones and vitamin D
Glucocorticoid & Mineralcorticoid Metabolism
References
Ref 531312Current and future drug targets in weight management. Pharm Res. 2011 Aug;28(8):1792-818.
Ref 531312Current and future drug targets in weight management. Pharm Res. 2011 Aug;28(8):1792-818.

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