Drug Information

Drug General Information
Drug ID
D0E3ET
Former ID
DNC008713
Drug Name
AM-1714
Drug Type
Small molecular drug
Indication Discovery agent Investigative [529170]
Structure
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2D MOL

3D MOL
Formula
C22H26O4
Canonical SMILES
CCCCCCC(C)(C)C1=CC2=C(C(=C1)O)C3=C(C=CC(=C3)O)C(=O)O2
InChI
1S/C22H26O4/c1-4-5-6-7-10-22(2,3)14-11-18(24)20-17-13-15(23)8-9-16(17)21(25)26-19(20)12-14/h8-9,11-13,23-24H,4-7,10H2,1-3H3
InChIKey
BWKBVEVEQOCSCF-UHFFFAOYSA-N
PubChem Compound ID
9950486
Target and Pathway
Target(s) Cannabinoid receptor 2 Target Info Inhibitor [529170]
Cannabinoid receptor 1 Target Info Inhibitor [529170]
KEGG Pathway Neuroactive ligand-receptor interactionhsa04015:Rap1 signaling pathway
Neuroactive ligand-receptor interaction
Retrograde endocannabinoid signaling
PANTHER Pathway Endogenous cannabinoid signaling
Pathway Interaction Database N-cadherin signaling events
Reactome Class A/1 (Rhodopsin-like receptors)
G alpha (i) signalling eventsR-HSA-373076:Class A/1 (Rhodopsin-like receptors)
G alpha (i) signalling events
WikiPathways GPCRs, Class A Rhodopsin-like
Small Ligand GPCRs
GPCR ligand binding
GPCR downstream signalingWP455:GPCRs, Class A Rhodopsin-like
BDNF signaling pathway
GPCR downstream signaling
GPCRs, Other
References
Ref 529170J Med Chem. 2007 Dec 27;50(26):6493-500. Epub 2007 Nov 27.Cannabilactones: a novel class of CB2 selective agonists with peripheral analgesic activity.
Ref 529170J Med Chem. 2007 Dec 27;50(26):6493-500. Epub 2007 Nov 27.Cannabilactones: a novel class of CB2 selective agonists with peripheral analgesic activity.

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