Drug General Information
Drug ID	D0E3ST
Former ID	DNC007939
Drug Name	1-(4-ethylpiperazin-1-yl)-2-phenylethanone
Drug Type	Small molecular drug
Indication	Discovery agent		Investigative	[528722]
Structure		Download 2D MOL 3D MOL
Formula	C14H20N2O
Canonical SMILES	CCN1CCN(CC1)C(=O)CC2=CC=CC=C2
InChI	1S/C14H20N2O/c1-2-15-8-10-16(11-9-15)14(17)12-13-6-4-3-5-7-13/h3-7H,2,8-12H2,1H3
InChIKey	ZKLSFAKJJJDQSA-UHFFFAOYSA-N
PubChem Compound ID	3328378
Target and Pathway
Target(s)	Corticosteroid 11-beta-dehydrogenase, isozyme 1	Target Info	Inhibitor	[528722]
KEGG Pathway	Steroid hormone biosynthesis
	Metabolism of xenobiotics by cytochrome P450
	Metabolic pathways
	Chemical carcinogenesis
NetPath Pathway	IL1 Signaling Pathway
	FSH Signaling Pathway
PathWhiz Pathway	Steroidogenesis
Reactome	Glucocorticoid biosynthesis
WikiPathways	Prostaglandin Synthesis and Regulation
	Metabolism of steroid hormones and vitamin D
	Glucocorticoid & Mineralcorticoid Metabolism
References
Ref 528722	Bioorg Med Chem Lett. 2007 May 15;17(10):2838-43. Epub 2007 Feb 25.Discovery and biological evaluation of adamantyl amide 11beta-HSD1 inhibitors.
Ref 528722	Bioorg Med Chem Lett. 2007 May 15;17(10):2838-43. Epub 2007 Feb 25.Discovery and biological evaluation of adamantyl amide 11beta-HSD1 inhibitors.

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