TTD | Drug: D0E4AK

Drug General Information
Drug ID	D0E4AK
Former ID	DIB018347
Drug Name	[3H]MRS2279
Synonyms	[3H]-MRS2279
Drug Type	Small molecular drug
Indication	Discovery agent		Investigative	[539078]
Structure		Download 2D MOL
Formula	C13H20ClN5O8P2
InChI	InChI=1S/C13H20ClN5O8P2/c1-15-11-10-12(18-13(14)17-11)19(6-16-10)4-7-2-8(5-26-28(20,21)22)9(3-7)27-29(23,24)25/h6-9H,2-5H2,1H3,(H,15,17,18)(H2,20,21,22)(H2,23,24,25)/t7-,8-,9+/m1/s1
InChIKey	LPZJKPSGEADHTQ-HLTSFMKQSA-N
PubChem Compound ID	5311301
PubChem Substance ID	7980036, 39340999, 51311316, 57359425, 114155781, 135650656, 135651183
Target and Pathway
Target(s)	P2Y purinoceptor 1	Target Info	Antagonist	[526444]
KEGG Pathway	Rap1 signaling pathway
	Neuroactive ligand-receptor interaction
	Platelet activation
Reactome	G alpha (q) signalling events
	P2Y receptors
	ADP signalling through P2Y purinoceptor 1
WikiPathways	Nucleotide GPCRs
	GPCRs, Class A Rhodopsin-like
	Gastrin-CREB signalling pathway via PKC and MAPK
	Signal amplification
	GPCR ligand binding
	GPCR downstream signaling
References
Ref 539078	(http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 1727).
Ref 526444	Quantitation of the P2Y(1) receptor with a high affinity radiolabeled antagonist. Mol Pharmacol. 2002 Nov;62(5):1249-57.

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Drug Information