Drug General Information
Drug ID	D0E5EB
Former ID	DIB020046
Drug Name	impentamine
Synonyms	PDSP1_000940; PDSP2_000926
Drug Type	Small molecular drug
Indication	Discovery agent		Investigative	[538767]
Structure		Download 2D MOL
Formula	C8H15N3
InChI	InChI=1S/C8H15N3/c9-5-3-1-2-4-8-6-10-7-11-8/h6-7H,1-5,9H2,(H,10,11)
InChIKey	MZCJWLAXZRFUPI-UHFFFAOYSA-N
PubChem Compound ID	9793868
PubChem Substance ID	14747940, 24695045, 29215512, 44829892, 47731253, 48179721, 49846722, 50076869, 78799041, 85219085, 103184400, 103856708, 128668611, 135650386, 137132872, 162516569, 233425680, 234647720
Target and Pathway
Target(s)	Histamine H3 receptor	Target Info	Agonist	[526894]
KEGG Pathway	Neuroactive ligand-receptor interaction
Reactome	Histamine receptors
	G alpha (i) signalling events
WikiPathways	Monoamine Transport
	GPCRs, Class A Rhodopsin-like
	GPCR ligand binding
	GPCR downstream signaling
References
Ref 538767	(http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 1252).
Ref 526894	Synthesis and structure-activity relationships of conformationally constrained histamine H(3) receptor agonists. J Med Chem. 2003 Dec 4;46(25):5445-57.

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