| Drug General Information |
| Drug ID |
D0E5HC
|
| Former ID |
DNC003343
|
| Drug Name |
3-(5-methoxy-1H-indol-3-yl)propanoic acid
|
| Drug Type |
Small molecular drug
|
| Indication |
Discovery agent
|
Investigative |
[1]
|
|---|
| Structure |
|
Download
2D MOL
3D MOL
|
| Formula |
C12H13NO3
|
| Canonical SMILES |
COC1=CC2=C(C=C1)NC=C2CCC(=O)O
|
| InChI |
1S/C12H13NO3/c1-16-9-3-4-11-10(6-9)8(7-13-11)2-5-12(14)15/h3-4,6-7,13H,2,5H2,1H3,(H,14,15)
|
| InChIKey |
ZLSZCJIWILJKMR-UHFFFAOYSA-N
|
| PubChem Compound ID |
|
| PubChem Substance ID |
3433908, 4513020, 8112355, 10259373, 11177116, 11217585, 17476508, 24300031, 25630112, 33503968, 47487473, 57244469, 77899824, 89128767, 92236459, 99247359, 99444194, 104433802, 104847627, 117676131, 124663390, 125603589, 129920970, 135160777, 135586904, 137044037, 139622370, 143415823, 143802578, 160968790, 162516459, 169571045, 179179637, 223926267, 229078986, 249804210, 251875984, 252456062, 252471783
|
| Target and Pathway |
| Target(s) |
Peroxisome proliferator activated receptor gamma |
Target Info |
Inhibitor |
[1]
|
|---|
|
KEGG Pathway
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PPAR signaling pathway
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AMPK signaling pathway
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Osteoclast differentiation
|
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Huntington's disease
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Pathways in cancer
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Transcriptional misregulation in cancer
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Thyroid cancer
|
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NetPath Pathway
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IL1 Signaling Pathway
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TGF_beta_Receptor Signaling Pathway
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Leptin Signaling Pathway
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PANTHER Pathway
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CCKR signaling map ST
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Pathway Interaction Database
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Noncanonical Wnt signaling pathway
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Calcineurin-regulated NFAT-dependent transcription in lymphocytes
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Signaling events mediated by HDAC Class I
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RXR and RAR heterodimerization with other nuclear receptor
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Regulation of retinoblastoma protein
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Reactome
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PPARA activates gene expression
|
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Transcriptional regulation of white adipocyte differentiation
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Nuclear Receptor transcription pathway
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WikiPathways
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Wnt Signaling Pathway Netpath
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Nuclear Receptors in Lipid Metabolism and Toxicity
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Differentiation of white and brown adipocyte
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Regulation of Lipid Metabolism by Peroxisome proliferator-activated receptor alpha (PPARalpha)
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Transcriptional Regulation of White Adipocyte Differentiation
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Adipogenesis
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SREBP signalling
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Nuclear Receptors
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| References |
| REF 1 | The Protein Data Bank. Nucleic Acids Res. 2000 Jan 1;28(1):235-42. |
|---|
