Drug Information

Drug General Information
Drug ID
D0E9SR
Former ID
DIB018311
Drug Name
[3H]JNJ 7777120
Synonyms
[3H]-JNJ7777120
Drug Type
Small molecular drug
Indication Discovery agent Investigative [538791]
Structure
Download
2D MOL

3D MOL
Formula
C14H16ClN3O
InChI
InChI=1S/C14H16ClN3O/c1-17-4-6-18(7-5-17)14(19)13-9-10-8-11(15)2-3-12(10)16-13/h2-3,8-9,16H,4-7H2,1H3
InChIKey
HUQJRYMLJBBEDO-UHFFFAOYSA-N
PubChem Compound ID
4908365
PubChem Substance ID
7208642, 8472987, 14799535, 29217572, 39075314, 49846380, 50075249, 57357288, 57818501, 61262560, 78047416, 81123443, 85083127, 89501661, 103361356, 113628387, 125299313, 125333903, 131693053, 134343094, 135262061, 135650446, 135651168, 135697623, 137014298, 143295275, 162009834, 162012011, 162248412, 163123369, 167272760, 174529437, 184629548, 187071988, 198975186, 204370503, 223835200, 226546411, 246996609, 249776624, 250134239, 251970998, 252157719, 252160038, 252450534, 252472158
Target and Pathway
Target(s) Histamine H4 receptor Target Info Antagonist [526927]
KEGG Pathway Neuroactive ligand-receptor interaction
Reactome Histamine receptors
G alpha (i) signalling events
WikiPathways GPCR ligand binding
GPCR downstream signaling
GPCRs, Other
References
Ref 538791(http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 1279).
Ref 526927A potent and selective histamine H4 receptor antagonist with anti-inflammatory properties. J Pharmacol Exp Ther. 2004 Apr;309(1):404-13. Epub 2004 Jan 13.

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