Drug General Information
Drug ID	D0EG1F
Former ID	DIB008799
Drug Name	GR-199114X
Drug Type	Small molecular drug
Indication	Stomach ulcer [ICD10:K25-K27]		Terminated	[546618]
Company	Glaxo Wellcome plc
Structure		Download 2D MOL 3D MOL
Formula	C28H32FN5O4
Canonical SMILES	N1(C(=O)[C@@H](C(=O)N(c2c1cccc2)C1CCCCC1)NC(=O)Nc1ccc(F<br />)cc1)CC(=O)N1CCCC1
CAS Number	CAS 162271-54-7
PubChem Compound ID	9914672
Target and Pathway
Target(s)	Gastrin/cholecystokinin type B receptor	Target Info	Modulator	[546619]
KEGG Pathway	Calcium signaling pathway
	Neuroactive ligand-receptor interaction
	Gastric acid secretion
PANTHER Pathway	CCKR signaling map ST
PathWhiz Pathway	Gastric Acid Production
Reactome	Peptide ligand-binding receptors
	G alpha (q) signalling events
	Gastrin-CREB signalling pathway via PKC and MAPK
WikiPathways	GPCRs, Class A Rhodopsin-like
	Gastrin-CREB signalling pathway via PKC and MAPK
	Secretion of Hydrochloric Acid in Parietal Cells
	Peptide GPCRs
	GPCR ligand binding
	GPCR downstream signaling
	GPCRs, Other
References
Ref 546618	Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800009210)
Ref 546619	Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800009210)

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